Elabscience

EIF3I Polyclonal Antibody

Product Code:
 
E-AB-92730
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using EIF3I Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using EIF3I Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92730-60uL60uL£210.00
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E-AB-92730-120uL120uL£291.00
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E-AB-92730-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
EIF3I
Background:
Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
36kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human EIF3I
ObservedMW:
37kDa
Purification method:
Affinity purification
Target Synonym:
EIF3I;EIF3S2;PRO2242;TRIP-1;TRIP1;eIF3-beta;eIF3-p36
UNIProt ID:
Q13347

Documents