Elabscience

DUOX1 Polyclonal Antibody

Product Code:
 
E-AB-92892
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using DUOX1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using DUOX1 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92892-60uL60uL£210.00
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E-AB-92892-120uL120uL£291.00
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E-AB-92892-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
DUOX1
Background:
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
137kDa/177kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human DUOX1
ObservedMW:
180kDa
Purification method:
Affinity purification
Target Synonym:
DUOX1;LNOX1;NOXEF1;THOX1
UNIProt ID:
Q9NRD9

Documents