Elabscience

MAPK8IP1 Polyclonal Antibody

Product Code:
 
E-AB-92930
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using MAPK8IP1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using MAPK8IP1 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92930-60uL60uL£210.00
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E-AB-92930-120uL120uL£291.00
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E-AB-92930-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
MAPK8IP1
Background:
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
77kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000
Immunogen:
Recombinant fusion protein of human MAPK8IP1
ObservedMW:
78kDa
Purification method:
Affinity purification
Target Synonym:
MAPK8IP1;IB1;JIP-1;JIP1;PRKM8IP
UNIProt ID:
Q9UQF2

Documents