Elabscience

Recombinant Human SIGLEC2/CD22 Protein (His Tag)

Product Code:
 
PDMH100024
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
1 / 1

No additional charges, what you see is what you pay! *

CodeSizePrice
PDMH100024-20ug20ug£178.00
Quantity:
PDMH100024-100ug100ug£237.00
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
SIGLEC2;CD22
Accession:
P20273
Background:
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Calculated MW:
76.2 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
100-140 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asp20-Arg687
Target Synonym:
B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD22 antigenMGC130020;CD22 molecule;CD22;sialic acid binding Ig-like lectin 2;Siglec-2;SIGLEC2FLJ22814;T-cell surface antigen Leu-14;SIGLEC-2;Siglec-2
UNIProt ID:
P20273

Documents