Elabscience

Recombinant Human ILT4/LILRB2 protein (His tag)

Product Code:
 
PDMH100140
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PDMH100140-20ug20ug£178.00
Quantity:
PDMH100140-100ug100ug£237.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
ILT4;LILRB2
Accession:
Q8N423
Background:
Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa transmenbrane segment, and a 116 aa cytoplasmic domain. LIR-2 binds to Classical MHCI proteins. Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs, a requirement for association with SHP-1. LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo.
Calculated MW:
50.6 kDa
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
75 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Val461
Target Synonym:
Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2;LIR-2;Leukocyte Immunoglobulin-Like Receptor 2;CD85 Antigen-Like Family Member D;Immunoglobulin-Like Transcript 4;ILT-4;Monocyte/Macrophage Immunoglobulin-Like Receptor 10;MIR-10;CD85d;L
UNIProt ID:
Q8N423

Documents