NSJ Bioreagents

SREBP1 Antibody

Product Code:
 
NSJ-V8099SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
SREBP1/1578
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Store the SREBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 2
SDS-PAGE analysis of purified, BSA-free SREBP1 antibody (clone SREBP1/1578) as confirmation of integrity and purity.~
2 / 2
IHC staining of FFPE human ovarian carcinoma with SREBP1 antibody (clone SREBP1/1578). HIER: boil tissue sections in pH
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SDS-PAGE analysis of purified, BSA-free SREBP1 antibody (clone SREBP1/1578) as confirmation of integrity and purity.~
IHC staining of FFPE human ovarian carcinoma with SREBP1 antibody (clone SREBP1/1578). HIER: boil tissue sections in pH

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NSJ-V8099SAF-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant full-length human protein was used as the immunogen for this SREBP1 antibody.
Limitation:
This SREBP1 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Uniprot #:
P36956

Documents