NSJ Bioreagents

TGF alpha Antibody

Product Code:
 
NSJ-V9085SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
SPM357
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the TGF-a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC staining of FFPE human testicular carcinoma with TGF-a antibody (clone SPM357). HIER: pH 9 10mM Tris with 1mM EDTA.
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IHC staining of FFPE human testicular carcinoma with TGF-a antibody (clone SPM357). HIER: pH 9 10mM Tris with 1mM EDTA.

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NSJ-V9085SAF-100UG100 ug£534.00
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-a is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A 17-amino acid peptide from the C-terminus of the rat protein was used as the immunogen for this TGF a antibody.
Limitation:
This TGF-a antibody is available for research use only.
Localization:
Cytoplasmic and Extracellular (secreted)
Purity:
Protein G affinity chromatography
Uniprot #:
P01135

Documents