NSJ Bioreagents

Lambda Light Chain Antibody / Lambda Antibody

Product Code:
 
NSJ-V7879SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Recombinant Antibody
Antibody Clone:
 
LLC/3778R
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the recombinant Lambda antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 3
IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
2 / 3
IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
3 / 3
SDS-PAGE analysis of purified, BSA-free recombinant Lambda antibody (clone LLC/3778R) as confirmation of integrity and purity.
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IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Lambda antibody (clone LLC/3778R) as confirmation of integrity and purity.

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CodeSizePrice
NSJ-V7879SAF-100UG100 ug£534.00
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Further Information

Application Details:
Immunohistochemistry (FFPE): 0.1-0.2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant full-length human IGL protein was used as the immunogen for the recombinant Lambda antibody.
Limitation:
This recombinant Lambda antibody is available for research use only.
Localization:
Cell surface, cytoplasmic, secreted
Purity:
Protein A affinity chromatography
Uniprot #:
P01701, P01842

Documents