NSJ Bioreagents

Lambda Light Chain Antibody / Lambda Antibody

Product Code:
 
NSJ-V3262SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
LLC/1738
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the Lambda Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC testing of FFPE human tonsil stained with Lambda Light Chain antibody (clone LLC/1738). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
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IHC testing of FFPE human tonsil stained with Lambda Light Chain antibody (clone LLC/1738). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

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NSJ-V3262SAF-100UG100 ug£534.00
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Further Information

Application Details:
Immunohistochemistry (FFPE): 0.1-0.2ug/ml for 30 min at RT
Application Note:
The optimal dilution of the Lambda Light Chain antibody for each application should be determined by the researcher.
Description:
This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Purified human lambda light chain was used as the immunogen for this Lambda Light Chain antibody.
Limitation:
This Lambda Light Chain antibody is available for research use only.
Localization:
Cell Surface, Cytoplasmic and Secreted
Purity:
Protein G affinity chromatography
Uniprot #:
P01701, P01842

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