NSJ Bioreagents

Lambda Light Chain Antibody / Lambda Antibody

Product Code:
 
NSJ-V2153CF488
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
LcN-2
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
Storage:
 
Store the Lambda Light Chain antibody at 2-8oC protected from light.
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(Left) Immunofluorescent staining of permeabilized human Ramos cells with CF488-labeled Lambda Light Chain antibody (clone LcN-2, green) and DAPI (blue). (Right) Negative control.
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(Left) Immunofluorescent staining of permeabilized human Ramos cells with CF488-labeled Lambda Light Chain antibody (clone LcN-2, green) and DAPI (blue). (Right) Negative control.

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NSJ-V2153CF488-100T100 Tests£534.00
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This product comes from: United States.
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Further Information

Application Details:
Flow cytometry: 5ul per test per one million cells in 0.1ml or 5ul per 100ul of whole blood,Immunofluorescence: 1-2ug/ml
Application Note:
Optimal dilution of the Lambda Light Chain antibody should be determined by the researcher.
Description:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Format:
CF488 Conjugate
Formulation:
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Purified human Ig was used as the immunogen for this Lambda Light Chain antibody.
Limitation:
This Lambda Light Chain antibody is available for research use only.
Localization:
Cell surface, cytoplasmic, secreted
Purity:
Protein G affinity chromatography
Uniprot #:
P01701, P01842

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