NSJ Bioreagents

Granzyme B Antibody

Product Code:
 
NSJ-V3845SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b lambda
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
GZMB/2403
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 1
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Granzyme B antibody (clone GZMB/2403). These results demonstrate the foremost specificity of the GZMB/2403 mAb.<BR>Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination w
❮❯

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Granzyme B antibody (clone GZMB/2403). These results demonstrate the foremost specificity of the GZMB/2403 mAb.<BR>Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination w

No additional charges, what you see is what you pay! *

CodeSizePrice
NSJ-V3845SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Application Details:
ELISA: 1-5ug/ml for coating (order BSA/sodium azide-free format)
Application Note:
Optimal dilution of the Granzyme B antibody should be determined by the researcher.
Description:
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'non-self' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant fragment (amino acids 73-187) from the human protein was used as the immunogen for the Granzyme B antibody.
Limitation:
This Granzyme B antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity chromatography
Uniprot #:
P10144

Documents