Diaclone

Mouse Anti-Human CD262 BioActive Antibody, Clone B-K29, Azide free

Product Code:
 
854.860.000
Product Group:
 
Primary Antibodies
Supplier:
 
Diaclone
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
B-K29
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Functional Study
 

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854.860.000200ug/200ul£232.00
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Further Information

Activity:
Neutralizes TRAIL induced apoptosis of U937 cell line
Antigen:
TRAIL R2 / DR5
Antigen Synonyms:
DR5 TRAIL R2
Biological Acivity:
Neutralizes TRAIL induced apoptosis of U937 cell line
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TRAIL R2/Fc chimera
Reactivity:
Human
Research Area:
ApoptosisCD Markers
Specificity:
Recognises a 42-46 kDa protein
Workshop:
VIII

References

  1. Chen J.-J. et al. J. Immunol.2008; 180(12): 8030-8039.. Proteasome Inhibitors Enhance TRAIL-Induced Apoptosis through the Intronic Regulation of DR5: Involvement of NF-{kappa}B and Reactive Oxygen Species-Mediated p53 Activation. https://www.ncbi.nlm.nih.gov/pubmed/18523266
  2. Sato K. et al. J Exp Med.2006; 203(1): 239-50.. TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. https://www.ncbi.nlm.nih.gov/pubmed/16418392
  3. Vermot-Desroches C. et al. Cell Immunol. 2005;236(1-2):86-91. Characterization of monoclonal antibodies directed against trail or trail receptors. https://www.ncbi.nlm.nih.gov/pubmed/16157319