Chemodex

Naphthol AS-MX phosphate

Product Code:
 
CDX-N0127
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +4°C, Long term: -20°C
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Chemical Structure

Chemical Structure

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CodeSizePrice
CDX-N0127-M500500 mg£80.00
Quantity:
CDX-N0127-G0011 g£126.00
Quantity:
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
3-[(2,4-Dimethylphenyl)carbamoyl]naphthalen-2-yl dihydrogen phosphate
Appearance:
White to off-white powder.
CAS:
1596-56-1
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Keep under inert gas.Very hygroscopic.
Hazards:
H315 - H319 - H335
InChi:
InChI=1S/C19H18NO5P/c1-12-7-8-17(13(2)9-12)20-19(21)16-10-14-5-3-4-6-15(14)11-18(16)25-26(22,23)24/h3-11H,1-2H3,(H,20,21)(H2,22,23,24)
InChiKey:
IOMLBTHPCVDRHM-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1596-56-1. Formula: C19H18NO5P. MW: BD9837. Naphthol AS-MX Phosphate is a fluorogenic substrate for alkaline phosphatases. Naphthol AS-MX Phosphate is converted to naphthol AS-MX displaying excitation/emission spectra of 388/512nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting and dot blot applications.
MDL:
MFCD00042711
Molecular Formula:
C19H18NO5P
Molecular Weight:
371.32
Package Type:
Vial
Precautions:
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Product Description:
Naphthol AS-MX Phosphate is a fluorogenic substrate for alkaline phosphatases. Naphthol AS-MX Phosphate is converted to naphthol AS-MX displaying excitation/emission spectra of 388/512nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting and dot blot applications.
Purity:
>99% (HPLC)
Signal Word:
Warning
SMILES:
O=C(NC1=C(C)C=C(C)C=C1)C2=CC3=CC=CC=C3C=C2OP(O)(O)=O
Solubility Chemicals:
Soluble in ethanol (50mg/ml) or water.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

Documents

References

(1) Z. Lojda, etal.; Histochemie 11, 13 (1967) | (2) G.G. Guilbault & A. Vaughan; Anal. Lett. 3, 1 (1970) | (3) A. Vaughan, et al.; Anal. Chem. 43, 721 (1971) | (4) A.S.H.De Jong, et al.; Histochem. J. 17, 1119 (1985) | (5) S. West, et al.; Anal. Biochem. 190, 254 (1990) | (6) R. Gillitzer, et al.; J. Histochem. Cytochem. 38, 307 (1990) | (7) E.J. Speel, et al.; J. Histochem. Cytochem. 40, 1299 (1992) | (8) J. Espada, et al.; Histochem. Cell Biol. 108, 481 (1997)