NSJ Bioreagents

MYCN Antibody

Product Code:
 
NSJ-V4899
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PCRP-MYCN-1A9
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
Storage:
 
Aliquot the MYCN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 2
Flow cytometry testing of PFA-fixed human HeLa cells with MYCN antibody (clone PCRP-MYCN-1A9) followed by goat anti-mouse IgG-CF488 (blue), Red = unstained cells.~
2 / 2
Analysis of a HuProt(TM) microarray containing more than 19,000 full-length

Flow cytometry testing of PFA-fixed human HeLa cells with MYCN antibody (clone PCRP-MYCN-1A9) followed by goat anti-mouse IgG-CF488 (blue), Red = unstained cells.~
Analysis of a HuProt(TM) microarray containing more than 19,000 full-length

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CodeSizePrice
NSJ-V4899-20UG20 ug£264.00
Quantity:
NSJ-V4899-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
ELISA (Order BSA-free format for coating),Flow cytometry: 1-2ug/million cells
Description:
The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant human MYCN protein (within amino acids 335-463) was used as the immunogen for the MYCN antibody.
Limitation:
This MYCN antibody is available for research use only.
Localization:
Nucleus
Purity:
Protein A/G affinity
Uniprot #:
P04198

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