TargetMol

4-P-PDOT

Product Code:
 
TAR-T14042
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T14042-1mg1mg£95.00
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TAR-T14042-5mg5mg£128.00
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TAR-T14042-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T14042-10mg10mg£161.00
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TAR-T14042-25mg25mg£250.00
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TAR-T14042-50mg50mg£402.00
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Quantity:
TAR-T14042-100mg100mg£567.00
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Further Information

Bioactivity:
4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
CAS:
134865-74-0
Formula:
C19H21NO
Molecular Weight:
279.38
Pathway:
GPCR/G Protein|Neuroscience
Purity:
0.9968
SMILES:
CCC(=O)NC1CC(C2=CC=CC=C2C1)C3=CC=CC=C3
Target:
MT Receptor|Melatonin Receptor

References

Christopher Browning, et al. Pharmacological characterization of human recombinant melatonin mt1 and MT2 receptors. British Journal of Pharmacology (2000) 129, 877-886. Dubocovich ML. Melatonin receptors: are there multiple subtypes? Trends Pharmacol Sci. 1995 Feb;16(2):50-6. Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75. hin EJ, et al. Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential. Int J Neuropsychopharmacol. 2014 Dec 30;18(6). pii: pyu105.