TargetMol

GJ071 oxalate

Product Code:
 
TAR-T31932
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T31932-1mg1mg£227.00
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TAR-T31932-5mg5mg£431.00
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TAR-T31932-1mL1 mL * 10 mM (in DMSO)£483.00
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TAR-T31932-10mg10mg£600.00
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TAR-T31932-25mg25mg£863.00
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TAR-T31932-50mg50mg£1,187.00
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Quantity:
TAR-T31932-100mg100mg£1,581.00
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Quantity:
TAR-T31932-500mg500mg£3,107.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
GJ071 oxalate is a Nonsense suppressor. Nonsense suppressors (NonSups) induce ?readthrough?, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into nascent polypeptide.
CAS:
1216676-34-4
Molecular Weight:
455.53
Purity:
1
SMILES:
O=C(O)C(=O)O.S=C(NCCCOCC)N1CCN(CC2=CC=C3OCOC3=C2)CC1

References

Lavin MF. Generating SM(a)RTer compounds for translation termination suppression in A-T and other genetic disorders. Mol Ther. 2013 Sep;21(9):1650-2. Du L, et al. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep;21(9):1653-60.