TargetMol

(±)18-HETE

Product Code:
 
TAR-T35467
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T35467-1mg1mgEnquire
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Further Information

Bioactivity:
(?)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. 18(R)-HETE at 1 uM completely blocks 20-HETE-induced vasoconstriction of renal arterioles.
CAS:
133268-58-3
Formula:
C20H32O3
Molecular Weight:
320.473
Purity:
0.98
SMILES:
CCC(O)CC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O