TargetMol

19,20-Epoxycytochalasin D

Product Code:
 
TAR-T35483
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for both) without inducing cytotoxicity in Vero cells. It is cytotoxic to BT-549, LLC-PK11, and P388 cells (IC50s = 7.84, 8.4, and 0.16 µM, respectively) but not SK-MEL, KB, or SKOV3 cells up to a concentration of 10 µM.
CAS:
191349-10-7
Molecular Weight:
523.626
Purity:
0.98
SMILES:
[H][C@@]12O[C@@]1([H])[C@@](C)(O)C(=O)[C@@H](C)C\C=C\[C@@]1([H])[C@H](O)C(=C)[C@@H](C)[C@@]3([H])[C@H](Cc4ccccc4)NC(=O)[C@@]13[C@@H]2OC(C)=O |t:14|