TargetMol

Sartorypyrone D

Product Code:
 
TAR-T36875
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-T36875-1mg1mgEnquire
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Further Information

Bioactivity:
Sartorypyrone D is a fungal metabolite that has been found inN. fischeri.1It inhibits NADH fumarate reductase (NFRD; IC50= 1.7 uM inA. suummitochondria) and NADH oxidase (IC50= 3 uM in bovine heart mitochondria). Sartorypyrone is active against the Gram-positive bacteriaB. subtilis,K. rhizophila, andM. smegmatisin disc assays.
CAS:
1801167-48-5
Formula:
C26H38O4
Molecular Weight:
414.586
Purity:
0.98
SMILES:
C\C(CC[C@@H]1C(=C)CC[C@H](O)C1(C)C)=C/CC\C(C)=C\Cc1c(O)cc(C)oc1=O

References

Kaifuchi, S., Mori, M., Nonaka, K., et al.Sartorypyrone D: A new NADH-fumarate reductase inhibitor produced by Neosartorya fischeri FO-5897J. Antibiot. (Tokyo)68(6)403-405(2015)