TargetMol

5(S),12(S)-DiHETE

Product Code:
 
TAR-T37649
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T37649-1mg1mgEnquire
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Further Information

Bioactivity:
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.
CAS:
79056-01-2
Formula:
C20H32O4
Molecular Weight:
336.472
Purity:
0.98
SMILES:
CCCCC\C=C/C[C@H](O)\C=C\C=C/C=C/[C@@H](O)CCCC(O)=O