TargetMol

tetranor-PGEM

Product Code:
 
TAR-T37773
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T37773-1mg1mgEnquire
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Further Information

Bioactivity:
tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 ug of tetranor-PGEM over a 24-hour period.[1]
CAS:
24769-56-0
Formula:
C16H24O7
Molecular Weight:
328.361
Purity:
0.98
SMILES:
O[C@@H]1CC(=O)[C@H](CCC(O)=O)[C@H]1CCC(=O)CCCCC(O)=O

References

Honda, H., Fukawa, K., and Sawabe, T. Influence of adjuvant arthritis on main urinary metabolites of prostaglandin F and E rats. Prostaglandins 19, 259-269 (1980). Hamberg, M. Inhibition of prostaglandin synthesis in man. Biochemical and Biophysical Research Communications 49, 720-726 (1972).