TargetMol

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea

Product Code:
 
TAR-T60124
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60124-1mg1mg£227.00
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TAR-T60124-2mg2mg£306.00
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TAR-T60124-5mg5mg£430.00
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TAR-T60124-1mL1 mL * 10 mM (in DMSO)£503.00
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TAR-T60124-10mg10mg£599.00
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TAR-T60124-25mg25mg£863.00
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TAR-T60124-50mg50mg£1,179.00
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TAR-T60124-100mg100mg£1,589.00
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Further Information

Bioactivity:
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.
CAS:
2379727-88-3
Formula:
C24H21ClF3N5O
Molecular Weight:
487.9
Pathway:
Apoptosis
Purity:
0.979
SMILES:
O=C(NC1=CC=C(Cl)C(=C1)C(F)(F)F)NC2CC=3C4=CC=C(C=C4NC3CC2)C=5C=NN(C5)C
Target:
TNF

References

Pei H, et al. Discovery of potent ureido tetrahydrocarbazole derivatives for cancer treatments through targeting tumor-associated macrophages. Eur J Med Chem. 2019 Dec 1;183:111741.