TargetMol

PBRM1-BD2-IN-2

Product Code:
 
TAR-T60156
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60156-1mg1mg£227.00
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Quantity:
TAR-T60156-1mL1 mL * 10 mM (in DMSO)£417.00
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Quantity:
TAR-T60156-5mg5mg£430.00
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Quantity:
TAR-T60156-10mg10mg£600.00
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Quantity:
TAR-T60156-25mg25mg£863.00
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Quantity:
TAR-T60156-50mg50mg£1,179.00
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Quantity:
TAR-T60156-100mg100mg£1,589.00
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Quantity:
TAR-T60156-500mg500mg£3,115.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PBRM1-BD2-IN-2 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-2 has binding affinity and inhibitory activity for PBRM1-BD2 with Kd and IC50 values of 9.3 uM and 1.0 uM, respectively. PBRM1-BD2-IN-2 can be used for the research of cancer.
CAS:
2819989-57-4
Molecular Weight:
311.14
Pathway:
Chromatin/Epigenetic
Purity:
1
SMILES:
O=C1NC(NC=2C=CC=C(Cl)C12)C=3C(F)=CC=CC3Cl
Target:
Epigenetic Reader Domain

References

Shifali Shishodia, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13.