TargetMol

Viloxazine

Product Code:
 
TAR-T60325
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T60325-1mg1mg£227.00
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TAR-T60325-5mg5mg£424.00
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TAR-T60325-10mg10mg£591.00
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TAR-T60325-25mg25mg£863.00
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TAR-T60325-50mg50mg£1,187.00
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TAR-T60325-100mg100mg£1,572.00
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TAR-T60325-500mg500mg£3,066.00
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Further Information

Bioactivity:
Viloxazine (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 uM and IC 50 = 27 uM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].
CAS:
46817-91-8
Formula:
C13H19NO3
Molecular Weight:
237.29
Pathway:
GPCR/G Protein|Neuroscience
Purity:
0.9982
SMILES:
O(C=1C=CC=CC1OCC2OCCNC2)CC
Target:
5-HT Receptor|Norepinephrine

References

Paw?owski L, et al. An evidence for the central serotoninergic activity of viloxazine. Pol J Pharmacol Pharm. 1979;31(4):261-269. Pinder RM, et al. Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1977;13(6):401-421. Yu C, et al. New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties. J Exp Pharmacol. 2020;12:285-300.