TargetMol

MAO-B-IN-9

Product Code:
 
TAR-T60671
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60671-1mg1mg£227.00
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Quantity:
TAR-T60671-1mL1 mL * 10 mM (in DMSO)£414.00
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Quantity:
TAR-T60671-5mg5mg£424.00
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Quantity:
TAR-T60671-10mg10mg£591.00
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Quantity:
TAR-T60671-25mg25mg£863.00
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Quantity:
TAR-T60671-50mg50mg£1,187.00
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Quantity:
TAR-T60671-100mg100mg£1,572.00
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Quantity:
TAR-T60671-500mg500mg£3,066.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 uM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-9 has neuroprotective effects against Aβ1-42-induced neuronal cell death, which may be related to the anti-aggregation effect of Aβ1-42.
CAS:
2416910-88-6
Molecular Weight:
300.4
Pathway:
Neuroscience
Purity:
0.9988
SMILES:
O=C(OC1CCN(CC#C)CC1)NC2=CC=C(C=C2)C(C)C
Target:
Monoamine Oxidase|Serotonin Transporter|Beta Amyloid

References

Ko?ak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 ; 197:112282.