TargetMol

TRPM4-IN-2

Product Code:
 
TAR-T61275
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-T61275-1mg1mg£113.00
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Quantity:
TAR-T61275-5mg5mg£173.00
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TAR-T61275-10mg10mg£240.00
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TAR-T61275-25mg25mg£444.00
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Quantity:
TAR-T61275-50mg50mg£711.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
TRPM4-IN-2, also known as NBA, is a highly effective inhibitor of transient receptor potential melastatin 4 (TRPM4). Its inhibitory potency is represented by an IC 50 value of 0.16 uM. This compound serves as a valuable tool in the investigation of prostate cancer and colorectal cancer [1] [2].
CAS:
667411-04-3
Molecular Weight:
355.77
Pathway:
Membrane transporter/Ion channel
Purity:
1
SMILES:
O=C(O)C1=CC=C(Cl)C=C1NC(=O)COC2=CC=CC=3C=CC=CC23
Target:
TRP/TRPV Channel

References

Stok?osa P, et al. Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers (Basel). 2021;13(21):5400. Borgstr?m A, et al. Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. J Mol Biol. 2021;433(17):166665.