TargetMol

dCeMM2

Product Code:
 
TAR-T61477
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61477-1mg1mg£95.00
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TAR-T61477-5mg5mg£128.00
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TAR-T61477-1mL1 mL * 10 mM (in DMSO)£160.00
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TAR-T61477-10mg10mg£168.00
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TAR-T61477-25mg25mg£282.00
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TAR-T61477-50mg50mg£431.00
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TAR-T61477-100mg100mg£606.00
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TAR-T61477-500mg500mg£1,211.00
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Further Information

Bioactivity:
dCeMM2 is a glue degrader. dCeMM2 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, leading to the ubiquitination and degradation of cyclin K.
CAS:
296771-07-8
Molecular Weight:
370.82
Pathway:
PROTAC
Purity:
0.9968
SMILES:
O=C(NC1=NC=C(Cl)C=C1)CSC=2N=NC3=C(N2)NC4=CC=CC=C34
Target:
Molecular Glues

References

Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling [published correction appears in Nat Chem Biol. 2021 Mar;17(3):361]. Nat Chem Biol. 2020;16(11):1199-1207.