TargetMol

Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine

Product Code:
 
TAR-T62750L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T62750L-1mg1mg£328.00
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TAR-T62750L-5mg5mg£696.00
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TAR-T62750L-10mg10mg£946.00
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TAR-T62750L-25mg25mg£1,372.00
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TAR-T62750L-50mg50mg£1,821.00
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Quantity:
TAR-T62750L-100mg100mg£2,424.00
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Further Information

Bioactivity:
rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 uM and an E.max value of > 250 uM for TREM2.
CAS:
2738485-99-7
Molecular Weight:
451.92
Purity:
1
SMILES:
CC1=NC=2C(=NC(=CC2N=C1C)[C@@H]3C[C@@H](OCC3)C4=CN(C)N=C4)C5=C(F)C=C(Cl)C=C5

References

White RD, et al. Preparation of heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use. WO2021226629 A1.