TargetMol

NRX-103095

Product Code:
 
TAR-T63730
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T63730-1mg1mg£342.00
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Quantity:
TAR-T63730-5mg5mg£728.00
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Quantity:
TAR-T63730-10mg10mg£978.00
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Quantity:
TAR-T63730-25mg25mg£1,428.00
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Quantity:
TAR-T63730-50mg50mg£1,894.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NRX-103095 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP and enhances the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 163 nM.
CAS:
2763260-38-2
Molecular Weight:
530.35
Pathway:
Stem Cells|Cytoskeletal Signaling
Purity:
0.9916
SMILES:
O=C(NC1=CC=CC(=C1)C(=O)N(C)C)C=2C(=O)NC(=CC2SC=3C(Cl)=CC=CC3Cl)C(F)(F)F
Target:
Wnt/beta-catenin

References

Kyle R Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402.