TargetMol

PF-04745637

Product Code:
 
TAR-T64337
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T64337-1mg1mg£160.00
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TAR-T64337-5mg5mg£269.00
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TAR-T64337-1mL1 mL * 10 mM (in DMSO)£293.00
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TAR-T64337-10mg10mg£348.00
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TAR-T64337-25mg25mg£539.00
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TAR-T64337-50mg50mg£740.00
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Quantity:
TAR-T64337-100mg100mg£994.00
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Quantity:
TAR-T64337-500mg500mg£1,910.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
CAS:
1917294-46-2
Molecular Weight:
509
Pathway:
Membrane transporter/Ion channel
Purity:
0.9791
SMILES:
OC(CC1)(CCN1C(Cc1ccccc1)CNC(C1(CCCC1)c(cc1)ccc1Cl)=O)C(F)(F)F
Target:
TRP/TRPV Channel

References

Laurie B. Schenkel, et al. The discovery of a potent series of carboxamide TRPA1 antagonists. J. Med. Chem. 2016, 59, 6, 2794-2809.