TargetMol

Dynamin IN-2

Product Code:
 
TAR-T64369
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T64369-1mg1mg£389.00
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TAR-T64369-5mg5mg£850.00
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TAR-T64369-1mL1 mL * 10 mM (in DMSO)£871.00
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TAR-T64369-10mg10mg£1,107.00
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TAR-T64369-25mg25mg£1,637.00
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TAR-T64369-50mg50mg£2,175.00
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Quantity:
TAR-T64369-100mg100mg£2,906.00
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Further Information

Bioactivity:
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 uM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 uM).
CAS:
1345853-49-7
Molecular Weight:
364.87
Pathway:
Cytoskeletal Signaling
Purity:
0.9881
SMILES:
ClC1=CC=C(C=C1)CNCC(O)CN2C=3C=CC=CC3C=4C=CC=CC42
Target:
Dynamin

References

Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.