TargetMol

SD49-7

Product Code:
 
TAR-T67781
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T67781-1mg1mg£206.00
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Quantity:
TAR-T67781-1mL1 mL * 10 mM (in DMSO)£389.00
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Quantity:
TAR-T67781-5mg5mg£390.00
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TAR-T67781-10mg10mg£540.00
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Quantity:
TAR-T67781-25mg25mg£823.00
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Quantity:
TAR-T67781-50mg50mg£1,091.00
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Quantity:
TAR-T67781-100mg100mg£1,452.00
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Quantity:
TAR-T67781-500mg500mg£2,825.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 uM.
CAS:
54009-54-0
Molecular Weight:
306.32
Pathway:
Chromatin/Epigenetic
Purity:
0.9936
SMILES:
O=C(NN=CC1=C(O)C=CC=2C=CC=CC21)C=3C=CC=CC3O
Target:
Histone Demethylase

References

Li Y, Wang C, Gao H, Gu J, Zhang Y, Zhang Y, Xie M, Cheng X, Yang M, Zhang W, Li Y, He M, Xu H, Zhang H, Ji Q, Ma T, Ding S, Zhao Y, Gao Y. KDM4 inhibitor SD49-7 attenuates leukemia stem cell via KDM4A/MDM2/p21CIP1 axis. Theranostics. 2022 Jun 21;12(11):4922-4934. doi: 10.7150/thno.71460. PMID: 35836814; PMCID: PMC9274755.