TargetMol

CYP4A11/CYP4F2-IN-2

Product Code:
 
TAR-T67916
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T67916-1mg1mg£106.00
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Quantity:
TAR-T67916-5mg5mg£148.00
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TAR-T67916-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T67916-10mg10mg£209.00
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Quantity:
TAR-T67916-25mg25mg£343.00
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Quantity:
TAR-T67916-50mg50mg£510.00
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Quantity:
TAR-T67916-100mg100mg£704.00
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Quantity:
TAR-T67916-500mg500mg£1,380.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
CYP4A11/CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50 values of 140 nM and 40 nM, respectively. CYP4A11/CYP4F2-IN-2 can be extracted from liver and kidney and has the potential to treat kidney diseases.
CAS:
2126874-77-7
Molecular Weight:
300.36
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C(N1CCC(COC=2C=NC(=CC2)C3=NNC=C3)CC1)C
Target:
P450

References

Kawamura M, et al. Discovery of Novel Pyrazolylpyridine Derivatives for 20-Hydroxyeicosatetraenoic Acid Synthase Inhibitors with Selective CYP4A11/4F2 Inhibition. J Med Chem. 2022;65(21):14599-14613.