TargetMol

Zoliprofen

Product Code:
 
TAR-T68025
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T68025-1mg1mg£132.00
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TAR-T68025-1mL1 mL * 10 mM (in DMSO)£208.00
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TAR-T68025-5mg5mg£214.00
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TAR-T68025-10mg10mg£287.00
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TAR-T68025-25mg25mg£477.00
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TAR-T68025-50mg50mg£625.00
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TAR-T68025-100mg100mg£859.00
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TAR-T68025-500mg500mg£1,653.00
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Further Information

Bioactivity:
Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat paw oedema, as well as anti-rat serum-induced fracture or dorsal skin oedema. Zoliprofen is 20 times more effective than ibuprofen and fenoprofen against collagen- or arachidonic acid-induced platelet aggregation in rats and rabbits. Zoliprofen was 20 times more effective than ibuprofen and fenoprofen in inhibiting endotoxin-induced diarrhoea in mice and arachidonic acid-induced acute mortality in rabbits.
CAS:
56355-17-0
Molecular Weight:
249.29
Purity:
0.979
SMILES:
O=C(O)C(C1=CC=C(OC2=NC=CS2)C=C1)C

References

Hong Dae Choi, et al. Synthesis of 4-(2-thiazolyloxy)phenylalkanoic acids as an antiinflammatory agent. 1996 ; 19: Archives of Pharmacal Research.148?152.