TargetMol

Dersalazine

Product Code:
 
TAR-T70084
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70084-1mg1mg£239.00
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TAR-T70084-5mg5mg£488.00
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TAR-T70084-10mg10mg£675.00
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TAR-T70084-25mg25mg£1,002.00
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TAR-T70084-50mg50mg£1,332.00
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TAR-T70084-100mg100mg£1,773.00
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Quantity:
TAR-T70084-500mg500mg£3,484.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dersalazine, an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential efficacy in patients with ulcerative colitis.
CAS:
188913-58-8
Molecular Weight:
600.68
Pathway:
Immunology/Inflammation|Others
Purity:
0.9942
SMILES:
CC1=NC2=CN=CC=C2N1CC3CCN(C(/C([H])=C(C4=CC=C(N=NC5=CC(C(O)=O)=C(O)C=C5)C=C4)\C6=CC=CC=C6)=O)CC3
Target:
IL Receptor|Platelet aggregation

References

Camuesco D, et al. The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis. Br J Pharmacol. 2012;165(3):729-740. Pontes C, et al. Safety and activity of dersalazine sodium in patients with mild-to-moderate active colitis: double-blind randomized proof of concept study. Inflamm Bowel Dis. 2014;20(11):2004-2012.