TargetMol

BI 1015550

Product Code:
 
TAR-T72031
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T72031-1mg1mg£118.00
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TAR-T72031-5mg5mg£173.00
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TAR-T72031-1mL1 mL * 10 mM (in DMSO)£193.00
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TAR-T72031-10mg10mg£229.00
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TAR-T72031-25mg25mg£389.00
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TAR-T72031-50mg50mg£544.00
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Quantity:
TAR-T72031-100mg100mg£748.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BI 1015550 is an orally active inhibitor of PDE4B with an IC 50 value of 7.2 nM. BI 1015550 has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD) .
CAS:
1423719-30-5
Molecular Weight:
448.97
Pathway:
Metabolism
Purity:
0.9806
SMILES:
N(C1=C2C(=NC(=N1)N3CCC(CC3)C=4N=CC(Cl)=CN4)CCS2=O)C5(CO)CCC5
Target:
PDE

References

Pouzet P A, et al. Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma. United States. US9150586. Herrmann FE, et al. BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis. Front Pharmacol. 2022;13:838449.