TargetMol

BTA-EG4 hydrate

Product Code:
 
TAR-T72074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T72074-1mg1mg£227.00
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Quantity:
TAR-T72074-5mg5mg£424.00
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TAR-T72074-10mg10mg£601.00
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TAR-T72074-25mg25mg£994.00
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Quantity:
TAR-T72074-50mg50mg£1,484.00
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Quantity:
TAR-T72074-100mg100mg£2,255.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BTA-EG4 hydrate can be used to diagnose, prevent or reduce the symptoms of amyloid-related diseases like Alzheimer's disease and can be used to improve cognitive function.
CAS:
921193-28-4
Molecular Weight:
416.53
Purity:
0.98
SMILES:
OCCOCCOCCOCCNC1=CC=C(C=C1)C2=NC=3C=CC(=CC3S2)C

References

Lee NJ, et al. Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway. Biochim Biophys Acta. 2016 ; 1862(2):284-295. Song JM, et al. A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease. Exp Neurol. 2014 ; 252:105-113. Chilumuri A, et al. Benzothiazole aniline tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro. ACS Chem Neurosci. 2013 ; 4(11):1501-1512. Prangkio P, et al. Self-assembled, cation-selective ion channels from an oligo(ethylene glycol) derivative of benzothiazole aniline. Biochim Biophys Acta. 2011 ; 1808(12):2877-2885. Croft CL, et al. Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer's disease. Sci Rep. 2017 ; 7(1):7434.