TargetMol

LJP-1586 HCl

Product Code:
 
TAR-T8857
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T8857-1mg1mg£227.00
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TAR-T8857-5mg5mg£431.00
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TAR-T8857-10mg10mg£613.00
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TAR-T8857-25mg25mg£870.00
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TAR-T8857-50mg50mg£1,235.00
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Quantity:
TAR-T8857-100mg100mg£1,637.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH).
CAS:
955037-42-0
Molecular Weight:
231.69
Purity:
0.994
SMILES:
C(/C(=C/F)/CN)C1=CC=C(OC)C=C1.Cl

References

Xu H, et al. VAP-1 blockade prevents subarachnoid hemorrhage-associated cerebrovascular dilating dysfunction via repression of a neutrophil recruitment-related mechanism. Brain Res. 2015 Apr 7;1603:141-9. Filip A, et al. Expression of the semicarbazide-sensitive amine oxidase in articular cartilage: its role in terminal differentiation of chondrocytes in rat and human. Osteoarthritis Cartilage. 2016 Jul;24(7):1223-34. Xu HL, et al. Pharmacologic blockade of vascular adhesion protein-1 lessens neurologic dysfunction in rats subjected to subarachnoid hemorrhage. Brain Res. 2014 Oct 24;1586:83-9. Watcharotayangul J, et al. Post-ischemic vascular adhesion protein-1 inhibition provides neuroprotection in a rat temporary middle cerebral artery occlusion model. J Neurochem. 2012 Nov;123 Suppl 2:116-24.