TargetMol

FiVe1

Product Code:
 
TAR-T9657
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T9657-1mg1mg£335.00
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TAR-T9657-5mg5mg£711.00
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Quantity:
TAR-T9657-1mL1 mL * 10 mM (in DMSO)£827.00
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TAR-T9657-10mg10mg£946.00
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TAR-T9657-25mg25mg£1,396.00
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TAR-T9657-50mg50mg£1,862.00
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Quantity:
TAR-T9657-100mg100mg£2,424.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase, leading to mitotic disasters, polynuclearization, and loss of cancer cell dryness. FiVe1 selectively and irreversibly inhibit the growth of mesenchymal transformed breast cancer cells (FOXC2-HMLER cell, IC50=234nM) and soft tissue sarcomas of different histological subtypes.
CAS:
932359-76-7
Molecular Weight:
359.25
Purity:
0.9878
SMILES:
ClC1=CC=CC(=C1)N2CCN(C3=CN=NC4=C(Cl)C=CC=C43)CC2

References

Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E991