TargetMol

GSK2850163 (S enantiomer)

Product Code:
 
TAR-T9848
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T9848-1mg1mg£227.00
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TAR-T9848-5mg5mg£431.00
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TAR-T9848-1mL1 mL * 10 mM (in DMSO)£470.00
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TAR-T9848-10mg10mg£600.00
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TAR-T9848-25mg25mg£863.00
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TAR-T9848-50mg50mg£1,187.00
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Quantity:
TAR-T9848-100mg100mg£1,581.00
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TAR-T9848-500mg500mg£3,107.00
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Further Information

Bioactivity:
GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a).
CAS:
2309519-81-9
Formula:
C24H29Cl2N3O
Molecular Weight:
446.41
Pathway:
Cell Cycle/Checkpoint
Purity:
0.984
SMILES:
Cc1ccc(CNC(=O)N2CCC[C@@]3(CCN(Cc4ccc(Cl)c(Cl)c4)C3)C2)cc1
Target:
IRE1

References

Nestor O. Concha, et al. Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1?Endoribonuclease Activity. Molecular Pharmacology December 2015, 88 (6) 1011-1023.