TargetMol

PKCiota-IN-2

Product Code:
 
TAR-T9863
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T9863-1mg1mg£227.00
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Quantity:
TAR-T9863-2mg2mg£306.00
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TAR-T9863-5mg5mg£431.00
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TAR-T9863-1mL1 mL * 10 mM (in DMSO)£465.00
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TAR-T9863-10mg10mg£600.00
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TAR-T9863-25mg25mg£863.00
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Quantity:
TAR-T9863-50mg50mg£1,187.00
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Quantity:
TAR-T9863-100mg100mg£1,581.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PKCiota-IN-2 is a selective and potent PKCiota (PKC-I) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively
CAS:
2230055-52-2
Molecular Weight:
395.46
Pathway:
Cytoskeletal Signaling|Chromatin/Epigenetic
Purity:
0.9974
SMILES:
N=1C=CC(C=2C=CN3N=CC(C=4C=C5C(=CC4OC)CCNC5)=C3C2)=C6C=CNC16
Target:
PKC

References

Jacek Kwiatkowski, et al. Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61(10):4386-4396.