TargetMol

3'-Methoxydaidzein

Product Code:
 
TAR-TN1254
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TN1254-1mg1mg£189.00
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TAR-TN1254-5mg5mg£367.00
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TAR-TN1254-10mg10mg£545.00
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TAR-TN1254-25mg25mg£821.00
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TAR-TN1254-50mg50mg£1,083.00
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Further Information

Bioactivity:
3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for collagen-induced platelet aggregation with IC50 values of 12.3 and 61.5uM, respectively. 3'-Methoxydaidzein acts as an analgesic by inhibiting voltage-gated sodium channels. 3'-Methoxydaidzein showed antioxidant activity and antiplatelet aggregation activity.
CAS:
21913-98-4
Formula:
C16H12O5
Molecular Weight:
284.26
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
O=C1C2=CC=C(O)C=C2OC=C1C=3C=CC(O)=C(OC)C3
Target:
Sodium Channel

References

Chang LC, et al. Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase. J Nat Prod. 1997;60(9):869-873. Xu RJ, et al. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. Chin J Nat Med. 2019;17(6):413-423. Wang W, et al. Antioxidant activities of natural phenolic components from Dalbergia odorifera T. ChenFood Chem. 2000;71(1):45-49.