TargetMol

ERCC1-XPF-IN-2

Product Code:
 
TAR-T60904
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60904-2mg2mg£98.00
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Quantity:
TAR-T60904-5mg5mg£115.00
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TAR-T60904-10mg10mg£148.00
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TAR-T60904-25mg25mg£229.00
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TAR-T60904-50mg50mg£334.00
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Quantity:
TAR-T60904-100mg100mg£470.00
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Quantity:
TAR-T60904-200mg200mg£627.00
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Quantity:
TAR-T60904-500mg500mg£938.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 uM [1].
CAS:
1808986-37-9
Molecular Weight:
326.17
Purity:
0.9834
SMILES:
O=C(NCC1=CC=C(O)C(O)=C1)CC2=CC=C(Cl)C=C2Cl

References

Chapman TM, et al. Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4097-103.