TargetMol

CCR1 antagonist 7

Product Code:
 
TAR-T10709
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T10709-5mg5mg£850.00
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Quantity:
TAR-T10709-50mg50mg£1,661.00
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Quantity:
TAR-T10709-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
CAS:
2446154-74-9
Formula:
C21H24ClN5O3S
Molecular Weight:
461.96
Pathway:
Microbiology/Virology|Immunology/Inflammation
Purity:
0.98
SMILES:
O=S(NC)(C1=NC=CC([C@@H](NC(C2=C(C)N(C3=CC=C(Cl)C=C3)N=C2)=O)CCC)=C1)=O
Target:
CCR

References

Harcken C, et al. Discovery and optimization of pyrazole amides as antagonists of CCR1. Bioorg Med Chem Lett. 2019 Feb 1;29(3):435-440.