TargetMol

Lipoxin B4

Product Code:
 
TAR-T37460
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T37460-5mg5mg£1,572.00
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TAR-T37460-50mg50mg£3,107.00
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TAR-T37460-100mg100mg£4,247.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.
CAS:
98049-69-5
Formula:
C20H32O5
Molecular Weight:
352.471
Purity:
0.98
SMILES:
CCCCC[C@H](O)[C@H](O)\C=C\C=C\C=C/C=C/[C@@H](O)CCCC(O)=O

References

Serhan, C.N., Hamberg, M., and Samuelsson, B. Lipoxins: Novel series of biologically active compounds formed from arachidonic acid in human leukocytes Proc. Natl. Acad. Sci. U.S.A. 81(17), 5335-5339 (1984). Papayianni, A., Serhan, C.N., and Brady, H.R. Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells Journal of Immunology 156, 2264-2272 (1996). Serhan, C.N., Hamberg, M., Samuelsson, B., et al. On the stereochemistry and biosynthesis of lipoxin B Proc. Nat. Acad. Sci. USA 83(7), 1983-1987 (1986).