TargetMol

MitoBloCK-6

Product Code:
 
TAR-T60143
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60143-5mg5mg£97.00
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Quantity:
TAR-T60143-10mg10mg£108.00
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Quantity:
TAR-T60143-25mg25mg£132.00
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Quantity:
TAR-T60143-50mg50mg£172.00
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Quantity:
TAR-T60143-100mg100mg£229.00
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Quantity:
TAR-T60143-200mg200mg£309.00
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Quantity:
TAR-T60143-500mg500mg£485.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC 50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 with IC 50 of 1.4 uM. MitoBloCK-6 can induce apoptosis via cytochrome c release in human embryonic stem cells (hESCs) [1].
CAS:
303215-67-0
Molecular Weight:
357.23
Pathway:
Apoptosis
Purity:
0.9814
SMILES:
ClC=1C=C(Cl)C(O)=C(C=NC2=CC=C(C=C2)NC=3C=CC=CC3)C1
Target:
Apoptosis

References

Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92.