TargetMol

AP-C5

Product Code:
 
TAR-T60500
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60500-5mg5mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T60500-10mg10mg£142.00
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Quantity:
TAR-T60500-25mg25mg£213.00
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Quantity:
TAR-T60500-50mg50mg£306.00
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Quantity:
TAR-T60500-100mg100mg£453.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AP-C5 is a compound with selective inhibition of guanosine 3',5' cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), with a Pic50 value of 7.2 for cGMP, and can be used in the study of diarrheal diseases.
CAS:
2234272-10-5
Molecular Weight:
275.31
Pathway:
Microbiology/Virology
Purity:
0.9919
SMILES:
C#CCNC1=NC=CC(=N1)C=2C=CC(=CC2)N3C=NC=C3
Target:
Parasite

References

Corvillo F, et al. Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy. Clin Exp Immunol. 2016;184(1):118-125. Bijvelds MJC, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018;293(21):8173-8181.