TargetMol

HIV-1 inhibitor-30

Product Code:
 
TAR-T61311
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61311-5mg5mg£850.00
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Quantity:
TAR-T61311-50mg50mg£1,661.00
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Quantity:
TAR-T61311-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM. Furthermore, HIV-1 inhibitor-30 demonstrates significant effectiveness against seven NNRTI-resistant strains of HIV-1 (RT-K103N; RT-Y181C; RT-K103N, Y181C; RT-L100I, K103N; RT-Y188L; RT-K103N, G190A; RT-K103N, V108I), with IC 50 values ranging from 0.04 to 1.42 uM. This compound holds potential for AIDS research [1].
CAS:
2132412-77-0
Molecular Weight:
357.84
Purity:
0.98
SMILES:
CCCCOn1cc(CC(=O)Nc2ccncc2Cl)c2ccccc12