TargetMol

Mt KARI-IN-2

Product Code:
 
TAR-T61570
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61570-5mg5mg£850.00
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Quantity:
TAR-T61570-50mg50mg£1,661.00
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Quantity:
TAR-T61570-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 uM. This compound also exhibits inhibitory activity against Mtb H37Rv, with a MIC value of 0.78 uM. Moreover, Mt KARI-IN-2 demonstrates low cytotoxicity, as evidenced by a HEK IC 50 greater than 86 ug/mL [1].
CAS:
2413974-52-2
Molecular Weight:
377.39
Purity:
0.98
SMILES:
COc1ccc(NC(=S)Nc2nnc(s2)-c2ccc(o2)[N+]([O-])=O)cc1