TargetMol

hCAI/II-IN-6

Product Code:
 
TAR-T61745
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61745-5mg5mg£125.00
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Quantity:
TAR-T61745-10mg10mg£158.00
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TAR-T61745-25mg25mg£253.00
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TAR-T61745-50mg50mg£366.00
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TAR-T61745-100mg100mg£545.00
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Quantity:
TAR-T61745-500mg500mg£1,083.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki values of 220, 4.9, 6.5, and >50,000 nM. hCAI/II-IN-6 showed anticonvulsant activity in vivo. hCAI/II-IN-6 can be used to study epilepsy. hCAI/II-IN-6 showed anticonvulsant activity in vivo. hCAI/II-IN-6 can be used to study epilepsy.
CAS:
694466-00-7
Formula:
C19H24N4O3S
Molecular Weight:
388.48
Pathway:
Metabolism
Purity:
0.9707
SMILES:
O=C(NC1=CC=C(C=C1)S(=O)(=O)N)CN2CCN(CC=3C=CC=CC3)CC2
Target:
Carbonic Anhydrase

References

Mishra CB, et al. Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. J Med Chem. 2017;60(6):2456-2469.